What we know

Respiratory infections such as colds, influenza and pneumonia affect millions of people around the world every year. Most cases are mild but some people can become very sick and are hospitalised.

What is this study exploring?

We are exploring why some people become more unwell than others and must be admitted to hospital in order to treat their respiratory infection. This study wants to determine how and why people respond to respiratory infections differently.

Why is this study important?

Currently it is not possible to predict who is at an increased risk of becoming severely ill by ARI’s within at risk groups. If this study can identify what groups of people are at a higher risk of becoming extremely ill from a respiratory infection, preventative and therapeutic interventions can be tailored for each individual, to prevent them from becoming very unwell.

What will the study involve for the participant?

The person will first be seen by a doctor or nurse as usual. The person taking part will be asked to answer some background questions and the doctor/nurse will do some non-invasive tests on them. On the first day the participant visits the GP/hospital, two days later and 28 days later the doctor/nurse will take nasal swabs and blood samples from them.

Who can take part?

Anyone over the age of 18, presenting with an acute respiratory infection between October and April in any of the 3 general practices and one hospital taking part in the study.

For more information

The HRB Primary Care Clinical Trials Network Ireland is coordinating the Irish component of the study. For more information please contact info@primarycaretrials.ie